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Dysregulation of iron metabolism is quite common in cancer cells

Although uncommon MM variants generally account for less than 2% of all melanomas [2,3,4,5,6], their prognosis is often poor, and their misdiagnosis may lead to potentially harmful handling errors associated with medical malpractice claims [7,8,9]

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It enables investigation of glucose regulation, appetite signaling, and gastrointestinal motility through GLP-1 receptor activation, supporting studies of incretin signaling pathways, energy balance regulation, and integrated central-peripheral metabolic communication