Metabolic improvements: blood sugar, A1C, cholesterol, and blood pressure Weight loss is visible
Introduction Your body is a complex biological engine that works around the clock to maintain balance
Research suggests that a meaningful portion of weight lost on GLP-1 medications may come from lean mass, not just fat
Cardiovascular and Other Benefits Weight loss gets the headlines, but the broader benefits of this class are arguably more important
Cardiometabolic markers (TRIUMPH-1, 80 weeks) This profile reads more like metabolic reprogramming than appetite suppression: Triglycerides: 41.0% Non-HDL cholesterol: 24.2% Systolic blood pressure: 12.3 mmHg Waist circumference: 24.1 cm (9.5 inches) What to Watch For: The Most Common Side Effects Retatrutides safety profile is broadly consistent with the GLP-1 class, with one genuinely new signal
Wilson-Perez HE, Chambers AP, Ryan KK, et al