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Proposed Mechanisms (Preclinical) ECM & Tissue Remodeling Explored for stimulation of collagen, elastin, and glycosaminoglycan synthesis in fibroblast and skin models
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A compound engineered to do the opposite, to push that pathway harder in order to grow synapses, is making a bet that you can rev a known cancer-promoting system in the brain without consequences elsewhere in the body, the same uncomfortable tradeoff we examined in our piece on whether peptides cause cancer
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Chauhan D, Tian Z, Zhou B, Kuhn D, Orlowski R, Raje N et al
10.1002/cne.901280110 J
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