On the practical question, the evidence points one way: combine at the point of use if at all one syringe or two, given close together and keep them as separate vials in storage, where there is no stability data to justify a pre-mixed blend
Specifically, bioactive food ingredients can activate or inhibit key enzymes and signaling pathways involved in metabolism, leading to improvements in lipid profiles, enhanced glucose metabolism, and better overall energy balance (1921)
Studies have shown that excessive HOCl/OH generation during neutrophil activation induces extensive DNA damage and subsequent DNA repair mechanisms which will result in NETosis [246, 247]
Since GSTs are indirectly involved in many metabolic reactions, the lack of such enzymes in susceptible subjects affects not only vitiligo but also other metabolic pathways where the enzyme function is necessary
Alp H, Orbak Z, Akcay F, Tan H, Aksoy H: Plasma and urine carnitine levels and carnitine supplementation in children with malnutrition
NAC may also reduce the formation of glutamate, an excitatory neurotransmitter that kills brain cells in excess