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On a different angle, when subjected to DEN-induced hepatocarcinogenesis, overexpression of PGC-1 renders mice more prone to hepatocarcinoma development possibly by enhancing the expression of genes involved in fatty acids and triglycerides synthesis as well as by limiting ROS accumulation via increased antioxidant response 12

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Supplementary Figure 5 Effect of apigenin on eryptosis levels of nave and P

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