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Those two unknowns were labelled as glucagon-like peptides: GLP-1 and GLP-2

This is important because nutritional needs and health goals vary widely from person to person, and personalized advice is necessary

Room temperature storage accelerates degradation over weeks to months

By substituting key amino acid residues, scientists have reduced susceptibility to enzymatic degradation, thereby extending the half-life of the molecule in experimental systems

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One strategy for extending the half-life of GLP-1 was therefore to develop formulations of DPP-4-resistant GLP-1 receptor activators