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10.18632/oncotarget.23737 Oncotarget 28 GrimmigB.HudsonC.MossL.PetersM.SubbarayanM.WeeberE

Supplementary Information The supplementary materials can be found in Supplementary information.pdf

Professor Albert Pinhasov of Ariel University emphasized the importance of balancing benefits with risks: We must acknowledge the potential risks highlighted in this study given the heterogeneity of the human population. Why Personalized Medicine is important Now More Than Ever One of the key takeaways of the study is the urgent need for genetic screening before prescribing GLP-1 receptor agonists

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Our data suggest that an alternative GLP-1R does not exist and that Glp1r -independent effects of GLP-1(7-36) and GLP-1(9-36) instead reflect the simultaneous response to other (related) GPCRs (that normally mediate the effects of other ligands such as glucagon)

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