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QR-110, an ASO drug in Phase III trials, was designed to address Leber congenital amaurosis type 10 caused by the p.Cys998X mutation in the centrosomal protein 290 gene

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Magnetic resonance imaging (MRI) of mice During the early monitoring period, mice were anesthetized with 2% isoflurane through a nose cone and the survival of fat grafts was evaluated using a 9.4-T small animal MRI scanner (BioSpec 94/30, Bruker, Billerica, MA, USA), while continuously monitoring the body temperature and respiratory rate of the mice