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veterans with type 2 diabetes and a pre-existing substance use disorder found that GLP-1 initiation was associated with roughly 40% lower risk of overdose compared to other diabetes medications

This will be on the lowest starting dose of 2.5mg

The Massachusetts General Hospital published guidance emphasizing that the most effective strategy for preserving lean body mass during GLP-1 therapy involves combining a high-protein diet with consistent resistance exercise

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Although preclinical studies reveal GLP-1 receptor expression within reproductive tissues and possible direct mechanisms, current human data remain inconclusive

Buteau J, Foisy S, Rhodes CJ, et al