The liquid takes up space and makes everything feel sloshy and gross
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Importantly, it does not significantly stimulate ACTH, cortisol, or prolactin release at physiological doses (PMID: 9849822)
On the other hand, poor dietary patternssuch as consuming high-fat foods, high-sugar foods, or ultra-processed foodscan reduce the effectiveness of GLP-1 agonists and increase gastrointestinal side effects
Dysesthesia was also reported, occurring in 8.8% of participants on 9 mg and 20.9% on 12 mg, compared with 0.7% on placebo
Hu M, Kong Z, Shi Q, Nie J