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Beyond their antioxidant functions, flavonoids contribute to stress adaptation by preserving enzymatic activity, supporting photosynthetic performance, and maintaining metabolic homeostasis under adverse environmental conditions ( NtCHS1 increases flavonoid accumulation and improves salinity tolerance ( LpFLS1 and LpCHI1 , and GmCHI4 in ryegrass and soybean sustains flavonoid biosynthesis under ionic stress (Zhang et al., 2024a)
Yajnik, C
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A recent study further demonstrated that proline catabolism via PRODH supports 3D growth of breast cancer cells, with elevated PRODH expression and proline oxidation in metastatic lesions compared with primary tumors, thereby promoting metastatic colonization and identifying PRODH as a potential target for metastasis suppression 64
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doi:10.1111/j.1365-2141.2009.07937.x
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