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Serious but rare risks include hypoglycemia (low blood sugar), acute pancreatitis (severe, persistent abdominal pain often with vomiting), acute gallbladder disease (sudden right-upper abdominal pain that may radiate to the shoulder), non-arteritic anterior ischemic optic neuropathy (sudden, potentially permanent vision loss), mood changes, and severe allergic reactions with breathing difficulty or swelling of the lips, tongue, or throat
PMID 35369081
It does not just mask the symptoms of histamine intolerance
10.1016/j.freeradbiomed.2025.01.010 100 WangD.LiangW.HuoD.WangH.WangY.CongC.et al (2023)
Can retatrutide be used by non-diabetic individuals
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