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BMC Biochem , 11: 3, 2010

Calcium-mobilizing derivatives of niacin The figure shows the chemical structures of calcium-mobilizing derivatives of niacin, including ADP-ribose, cyclic ADP-ribose, 2-deoxy-ADP-ribose, O-acetyl-ADP-ribose, and nicotinic acid adenine dinucleotide phosphate

First, its interplay with lipid metabolism: surplus pyruvate generated through glycolysis is converted to acetyl-CoA, which can enter lipid biosynthetic pathways and promote the synthesis of fatty acids, particularly PUFAs

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