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Lipoatrophy reduces the subcutaneous tissue available for injection, potentially forcing medication into muscle where absorption characteristics differ entirely
Smilkstein MJ, Knapp GL, Kulig KW, Rumack BH
PK: Conceptualization, Writing original draft, Writing review & editing
Popular tracking tools include: Patients can use simple charts or digital apps to record these numbers at home
Given levothyroxine's narrow therapeutic index, thyroid function should be reassessed 6-8 weeks after significant weight loss or if persistent gastrointestinal symptoms develop
Studies, including a 2022 trial on semaglutide, have shown that patients can regain a significant portion of their lost weight after discontinuing the medication
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