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Morphine and codeine should be avoided because they have been associated with numerous adverse effects, including HE and hypoglycemia.114 Despite recent reports against the use of tramadol and buprenorphine, more research is needed on patients with cirrhosis

r2: controlled for age, total calorie intake, physical activity level, medicine status, alcohol intake, smoking status

The safety and efficacy data in this population is limited because clinical trials specifically excluded them

Those are different numbers

Labs are generally normal during this period