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This results in increased stimulation of anorexigenic POMC/CART neurones and decreased activity of orexigenic NPY/AgRP neurones, profoundly altering appetite signals (Trapp and Brierley 2022)
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Key challenges include: Ensuring full traceability from supplier to final product
This highly regarded treatment is available as both an injection and a convenient oral pill
In one trial, adults who lost weight on tirzepatide for 36 weeks were switched to a placebo and followed for another year
But then to have all of that stare back, it's kind of like haha, you really didn't get rid of me
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