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By gene profiling of aorta samples and evaluation of anti-inflammatory properties of semaglutide in an acute in vivo inflammation model Rakipovski G, et al

GLP-1 receptor agonists are pharmacological agents designed to activate GLP-1 receptors, producing multiple clinically significant effects, including the stimulation of glucose-dependent insulin secretion from pancreatic beta cells, suppression of glucagon release, delayed gastric emptying, and enhanced peripheral glucose uptake

doi: 10.1002/lary.32061 67

The higher the DI above 2, the more the sample is considered to deviate from normobiosis

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