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Ann Intern Med
doi:10.1007/s10552-010-9620-8
How to Use Adults take 3 capsules daily, preferably with meals, or follow the direction on the product label
The TNG-CNPs (nitroglycerin-loaded chitosan nanoparticles) system releases NO slowly, activating the soluble guanylate cyclase (sGC)cGMP signaling pathway, thereby inhibiting NADPH oxidase activity, reducing O production, and upregulating eNOS expression, improving renal tissue perfusion status
Cysteine availability may then influence glutathione synthesis
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