Glucagon-like peptide-1 (GLP-1) is a naturally occurring hormone produced primarily by specialised L-cells in the lining of your small intestine and colon
T Jacque U
(Biochem Pharmacol, 2001) examined melanocortin peptides on NF-B DNA binding and nitric oxide production in RAW 264.7 macrophage-like cells and reported evidence for dual mechanisms of action
Other authors include Kyungsoo Kim, PhD, Matthew Murphy, PharmD, Owen Dougherty, Isis Christopher, Joseph Van Amburg, Kaylen Woodall, and Joey Barnett, PhD
Conclusions Use of GLP-1 receptor agonists was associated with reduced risk of a broad array of incident SUDs, suggesting potential preventive effects across a range of substances
Jia L, Qu P, Zhao Y, Bai L, Ren H, Cheng A