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24, 39, 40, 268, 269 A key issue for future clinical trial design will be to identify clinically relevant objective criteria for patient enrollment, and this remains a challenge, which has delayed a more aggressive approach of the pharmaceutical industry to identifying new treatment avenues for this condition

It imparts antioxidant benefits, which help to prevent premature aging and lend a youthful look

B12 is routinely sold in pharmacies, but prescription is needed