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It can be assumed that the remaining beta cells were protected by liraglutide treatment, and thereby beta cell degeneration was delayed
Based on these observations, we designed peptides in which the individual hydrophobic residues were substituted with alanine
Liraglutide reduced this renal outcome by 22% after 3.8 years follow up, whereas semaglutide showed a reduction of 36% after 2.1 years
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