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Oridonin, a diterpenoid compound isolated from Rabdosia rubescens , was shown to alleviate PI-IBS symptoms in rats by significantly inhibiting phosphorylation of NF-B p65 and downregulating downstream inflammatory mediators such as inducible nitric oxide synthase (iNOS), COX-2, IL-1, and IL-6

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Selective plasma free fatty acid panel analysis Aliquots of 20uL human serum were extracted by a bi-phasic solution of acidified methanol and isooctane, derivatized using PFBB, and analyzed by gas chromatographymass spectrometry (GC-MS) on an Agilent 6890N gas chromatograph equipped with an Agilent 7683 autosampler