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Genetic Predispositions in Antioxidant Pathways and Inflammation Genetic variants in genes encoding glutathione synthase (GCLC, GCLM), glutathione S-transferases (GSTs), and peroxiredoxins (PRDXs) influence how efficiently your body produces, recycles, and deploys glutathione

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A recent study reports that ferroptosis can promote tumor growth by driving macrophage polarization in the TME (Labiano et al., 2015)

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