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In mammalian cells, the caspase-3 is a 32 kDa inactive precursor requiring cleavage at specific aspartate residues to be converted into an active protease when cells receive the signal of apoptosis 18
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Gunay-Aygun M, Schwartz S, O'Riordan MA, Cassidy SB : The changing purpose of Prader-Willi syndrome clinical diagnostic criteria and proposed revised criteria
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