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These pathways are commonly studied in experimental models to understand how peptide signaling influences adipocyte function and energy metabolism

By isolating the C-terminus of the human growth hormone molecule (tyrosine at the 176th position to phenylalanine at the 191st), researchers can study the potent fat-burning properties of HGH without the confounding variables of insulin-like growth factor (IGF-1) elevation or decreased insulin sensitivity

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In a 23-week randomized clinical trial in humans, individuals taking AOD-9604 at 1 mg daily had an average of 2.8 kg weight reduction compared to a 0.8 kg weight reduction in those taking a placebo

A key safety advantage of AOD-9604: it does not bind or activate the growth hormone receptor [1]