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Glutathiones redox activity is essential for preventing damage to DNA, proteins and cell membranes that can accelerate cellular aging
This dynamic equilibrium is maintained by glutathione reductase, which regenerates GSH from GSSG using NADPH as a reducing agent
- Impact on blood sugar levels: MOTS-c has been shown to influence glucose metabolism
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A study published in the Proceedings of the National Academy of Sciences found that aging is associated with a 47% decrease in the catalytic subunit (GCLC) and a 52% decrease in the modulatory subunit (GCLM) of glutamate-cysteine ligase, the rate-limiting enzyme for glutathione production
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