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constructed berberine nanoparticles (BBR-NP), which significantly reduced ROS levels and regulated the Bax/Bcl-2 ratio, decreasing renal tubular epithelial cell apoptosis by 25%, while also reducing cytochrome C release and inhibiting Caspase-3 activation, thereby improving renal function [89]

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Koska J, Sands M, Burciu C, D'Souza KM, Raravikar K, Liu J, Truran S, Franco DA, Schwartz EA, Schwenke DC

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