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these include transient nausea and vomiting, abdominal cramps, and diarrhea

AOD-9604 completed six human trials enrolling more than 900 participants between the late 1990s and 2007

doi: 10.1007/s00125-013-3028-4 36 TamuraKMinamiKKudoMIemotoKTakahashiHSeinoS

Yadav P, Ortega JG, Tamaki W, Chien C, Chang KC, Biswas N, et al

A mode of action of glucosinolate-derived isothiocyanates: Detoxification depletes glutathione and cysteine levels with ramifications on protein metabolism in Spodoptera littoralis

Under certain conditions, GGT-mediated degradation of GSH facilitates the formation of reactive oxygen species, causing lipid peroxidation of cell membranes, which ultimately leads to apoptosis or necrosis of gastric epithelial cells in vitro 15