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Diabetes Obes Metab 22(8):12921301

Abstract Purpose of Review This review explores the rationale and available evidence behind incretin-based therapies for metabolic dysfunction-associated steatotic disease (MASLD) and metabolic-associated steatohepatitis (MASH), focusing on glucagon-like peptide 1 (GLP-1) and glucagon (GCG) receptor dual agonists (GLP-1/GCG RAs)

Drug repositioning or target repositioning: a structural perspective of drug-target-indication relationship for available repurposed drugs

Resources We Trust Cleveland Clinic: Metabolic Dysfunction-Associated Steatohepatitis (MASH) Mayo Clinic: Health Benefits of Semaglutide Beyond Weight Loss American Liver Foundation: MASLD and MASH Symptoms U.S

Ackermann RW, Hansen JB, Nauck M