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Common Actives GHK-Cu in studies outperformed tretinoin and vitamin C in procollagen synthesis, demonstrating a 70% response rate compared to 50% for vitamin C and 40% for tretinoin
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However, as with any medication affecting metabolic pathways, understanding its potential effects on various organ systemsincluding the eyesremains an important consideration for comprehensive patient care
In a rat model of neuropathic pain induced by tight ligation of L5/L6 spinal nerves, morroniside, administered either orally or intrathecally, dose-dependently alleviated mechanical allodynia, with comparable maximal efficacy (E max ) and an effective dose 50% (ED 50 ) values of 335 mgkg (oral) and 7.1 g (intrathecal) [73]
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Why Some People Don't Respond as Expected Assuming you're on a therapeutic dose and have given the medication sufficient time to work, several factors might explain a slower or minimal response: Individual biological variation plays a huge role
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