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The shorter, 10-20 day catagen phase, also known as a transitional state, begins to shut down hair growth

Mice were then divided into four weight-matched and liver function-matched groups (n=7 per group): NC group (C57BL/6 mice), Vehicle group (ob/ob mice), 50 mg/kg cinchonine group (ob/ob mice), and 100 mg/kg cinchonine group (ob/ob mice)

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Significant pain reduction typically occurs by weeks 2-3, with maximum benefits often achieved by week 6-8

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