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There were, the authors note, no head-to-head trials to compare the efficacy of the different medications
They are not reviewed by the FDA for safety, effectiveness, or manufacturing quality
doi: 10.1016/j.celrep.2021.109447 18 ZarseKRistowM
Quantitative analyses using high-resolution computed tomography (HRCT) confirm that IL-17A levels in severe COPD patients positively correlate with small airway disease and wall thickening (90)
The risk is real, but it is context-dependent
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