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The association of IGF-1 and IGF-1R apparently leads to changes in metabolism, prevention of cell death (apoptosis), promotion of cell growth (hypertrophy), differentiation and cell division (hyperplasia), normal development, and even malignant growth

The first is inconsistency, since stopping and starting or skipping doses interrupts the steady signal this stack depends on

doi: 10.1111/head.12725 7

Metabolic, Skin, and Mood Benefits Growth hormone and its related messenger, IGF-1, are involved in tissue repair, metabolism, and skin support

That's not research

Abdominal pain, particularly if severe, persistent, or radiating to the back, may indicate pancreatitisa rare but serious adverse effect requiring emergency evaluation