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The medicine slows gastric emptying what used to feel like a normal portion may now feel like overeating, and overeating while on a GLP-1 medicine can produce predictable nausea and discomfort

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I knew from my work with patients suffering from alcohol use disorder that this was remarkable given that there is no pharmacological treatment that I ever found effective for helping them

importantly, cumulative exposure (measured in pack-years) was strongly associated with fibrosis severity, with each additional pack-year tripling the likelihood of advanced fibrosis (adjusted OR per pack-year: 3.2