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Garate M et al
Active ingredients must pass through the skins outermost barrier, which typically allows only very small molecules to penetrate
Research suggests it encourages the breakdown of stored fat without significantly affecting blood sugar or acting through the IGF-1 pathway
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This process typically ramps up after 16 to 24 hours of fasting, though it begins on a smaller scale much earlier
Understanding these distinctions helps researchers make more informed decisions when evaluating available literature and designing future investigations
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