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Topical anti-aging effects are biologically plausible because collagen, glycosaminoglycans, skin elasticity, fibroblasts, and extracellular matrix remodeling are all directly relevant to skin aging [2], [4], [12]

During the IV she came back in the room every 15 min to check on me to see how I was feeling and making sure everything was going well

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All of them are small pilot studies

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