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A sweet or fruity urine odour may indicate ketosis, a metabolic state where the body breaks down fat for energy and excretes ketones through urine

But some experts worry that some patients who microdose may be acting unsafely

Important safety considerations include: Increased hypoglycaemia risk when used with insulin or sulfonylureas (dose adjustments of these medications may be needed) Potential worsening of diabetic retinopathy with rapid improvement in blood glucose control, particularly with semaglutide Need for monitoring in patients with pre-existing retinopathy The MHRA continues to monitor the safety profile of these agents

Are there other clinical trials of GLP-1 agonists in Parkinsons

Appendicitis is a time-sensitive diagnosis

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