DPP-4 inhibitors such as sitagliptin and saxagliptin increase endogenous GLP-1 concentration and demonstrate incretin-associated glucoregulatory actions in patients with T2DM
For patients with a naturally small cup-to-disc ratio, a structural characteristic of the optic nerve, the risk appears higher
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As these drugs become more accessible and democratized, as people get more comfortable taking them as a lifestyle choice, companies have to be there to support the consumer in that process, she says
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It does this by acting on a number of hormone pathways implicated in appetite and metabolism