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In experiments with Wistar rats fed a high-fat diet or treated with streptozotocin (STZ), ESC offered kidney protection by altering the renin-angiotensin system, decreasing histone H3 hyperacetylation at MCP-1 and TGF- gene promoters, and increasing H2AK119 monoubiquitination (a repressive mark) at these sites (Kushwaha et al
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TMAO
Importantly, just because you stop losing weight while taking a GLP-1 doesnt mean its stopped working
Supplementary information Supplementary Methods, Figs
Theyre not a cure-all
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