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Western blot analysis data presented that compared with the cells without treatment, the extent of p38 MAPK phosphorylation was increased in cells treated with CSE, and compared to CSE cells treated with PBS, it was reduced in CSE cells treated with NAC (Fig

Nguyen J, Remyn L, Chung IY, Honigman A, Gourani-Tehrani S, Wutami I, et al

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Int J Med Sci (2012) 9(2):18492

found that active GSH metabolism within tumors further suppresses immune responses, such as IFN- signaling and PD-1/PD-L1 interactions, while reducing the number of M1 macrophages and increasing the proportion of M2 macrophages