GLP-1 treatment adds meaningful benefit on top of that but wont replace it
Alternative treatments should be considered by pregnant women, nursing mothers, and people with asthma, sulfite allergies, or specific kidney/liver conditions
The mechanism and timeline are the same as for male patients, with some adjustments in the protocol for patients in perimenopause or menopause where hormonal changes affect collagen synthesis and healing rates
Participants using a GLP-1 RA had a greater reduction in HbA 1c 5.4 mmol/mol (0.5%) vs 2.6 mmol/mol (0.2%) and serum cholesterol (0.4 mmol/l vs 0.1 mmol/l) than those in the SGLT2i cohort
Before Medi losing weight has seemed like an impossible task
Some concerns were expressed by the deciding FDA panel regarding the safety of this drug in the long term, including its potential role in gallbladder disease, pancreatitis, increasing heart rate as well as concerns regarding thyroid and breast cancer