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This selective targeting underpins their efficacy in enhancing insulin secretion, inhibiting glucagon release, and promoting metabolic control in diabetes management (29)
When system x c - is inhibited, obstruction of the cystine transport pathway can decrease GSH and GPX4, which can lead to cell death due to ongoing oxidative stress ( Figure 1A )
Prevalence of residual B cell function and its metabolic consequences in type 1 (insulin-dependent) diabetes
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Sporadic dosing produces sporadic results
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