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Bordoni, L
In Drosophila melanogaster , the peptide reduced mitochondrial and cytosolic ROS levels, along with lipid peroxidation markers such as Schiff bases and hydroperoxides
Currently, excessive NNMT upregulation is implicated in several scenarios, including obesity, metabolic diseases, muscle cell degeneration, and even some types of cancer [2, 4]
Kojic acid, Glutathione
In contrast, PPAR-/ activates antioxidant genes like heme oxygenase-1 and quinone oxidoreductase-1 , enhancing cellular antioxidant defense (95)
Amer J, Goldfarb A, Fibach E
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