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Higher doses and more frequent shots may be needed for recovery

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The substantial weight reduction observed with tirzepatide monotherapy (15-21% body weight in clinical trials) suggests that any perceived benefits likely reflect tirzepatide's pharmacological effects rather than synergistic action

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It may achieve this through the following pathways

Payer policies change annually, and coverage criteria for Xiaflex can include step-edit requirements, like prior conservative treatment, that differ from one plan to the next