They block key enzymes, disrupt antioxidant systems, and generate free radicals
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Weiser MA, Cabanillas ME, Konopleva M, Thomas Da, Pierce Sa, Escalante CP et al
Factors released by neighbouring -cells or -cells amplify the glucose-induced effects on somatostatin secretion from -cells, which act locally within the islets as paracrine or autocrine inhibitors of insulin, glucagon and somatostatin secretion
FIGURE 3 Ferroptosis inhibitors and clinical application Ferroptosis inhibitors eliminate free radicals, inhibiting enzymes that produce lipids or LPOs and reducing free iron
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