Targeted Weight Loss Medication with Clinical Oversight Prescription weight loss medications are a core part of many of our programs, but they are never used in isolation
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For example, in non-dialysis CKD, paricalcitol did not reduce LV mass or improve cardiac function in PRIMO and OPERA despite biochemical effects, while in hemodialysis the J-DAVID trial found no reduction in cardiovascular events with oral alfacalcidol
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These drugs work by increasing the release of insulin, reducing appetite, and slowing down the digestion process, which can lead to weight loss