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The main reason that PPIs or antacids contribute to bacterial overgrowth is that they cause low stomach acid

Endoplasmic reticulum stress If not quickly rectified, any of the above stresses activates the ER stress- unfolded protein response (UPR) which, in turn, exacerbates oxidative stress and elicits inflammation by activating stress response genes such as NF-kB (9, 122)

Risk factors for SIBO include hypochlorhydria, motility disorders, irritable bowel syndrome, and medications such as proton pump inhibitors and histamine 2-receptor blockers

Alpha Lipoic Acid: Regenerates other antioxidants and combats oxidative stress

Nitric oxide-mediated protection of endothelial cells from hydrogen peroxide is mediated by intracellular zinc and glutathione

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