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Anyone who wants the original study can review the STEP 1 trial directly

Those with obesity are especially likely to develop it because their weight puts more stress on the knee and because obesity is associated with inflammation, which contributes to deterioration of cartilage

There are some side effects, and its a personal decision whether to take it or not, one that should be discussed with your healthcare team

They can help you with what to do next about the effects of semaglutide

It's studied for mobilizing stored fat (lipolysis) and blocking new fat storage (lipogenesis) through adipose-tissue pathways, without engaging appetite or insulin signaling

The danger is that normal blood glucose creates a false sense of safety, so the condition can progress undetected