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L-Carnitine supplementation an lead to improvements in several complications seen in uremic patients, including cardiac complications, impaired exercise and functional capacities, muscle symptoms, increased symptomatic intradialytic hypotension, and erythropoietin-resistant anemia through normalizing the reduced carnitine palmitoyl transferase activity in red cells [43]
10.1152/ajpregu.00590.2003 109 WiseR
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To reduce these potential risks, healthcare providers are advised to closely monitor patients, particularly those with a history of gallbladder or biliary disease [49]
However, there is limited data on how these risks may translate to humans
In a clinical trial that involved 153 obese (BMI 30 or greater) individuals, participants who were taking tirzepatide or other GLP-1 medications reported reduced cravings for alcohol and alcohol dependence as compared to non-alcoholics
