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Peters and Walsh used nafarelin acetate, the agonist of LH-RH, in men with symptomatic BPH and found an improvement, but upon cessation of treatment, the BPH symptoms returned 37

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As of April 22, 2026, it was removed from FDA Category 2, but the FDA's Pharmacy Compounding Advisory Committee will not consider it for the 503A bulks list until the July 23, 2026 meeting

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